The top ten times in history when using the "F" word was appropriate:

10 - "What the  *&%#  was that?" - Mayor of Hiroshima - August 1945

9 - "Where did all the  *&%#ing  Indians come from?" - Custer 1877

8 - "Any  *&%#ing  idiot could understand that." - Einstein 1938

7 - "It does SO  *&%#ing  look like her!" - Picasso 1926

6 -  "How the  *&%#  did you work that out?" - Pythagoras 126 BC

5 -  "You want WHAT on the  *&%#ing  ceiling?" - Michelangelo 1566

4 -  "I don't suppose it's gonna  *&%#ing  rain." - Joan of ARC 1434

3 -  "Scattered  *&%#ing  showers...my ass!" - Noah 314 BC

2 -  "I need this parade like I need a  *&%#ing  hole in the head!" - JFK 1963

and....drumroll.....

1 -  "Aw c'mon, who the  *&%#  is going to find out?  - Bill Clinton 1997